When you are not under the sweet influence of the Holy Spirit, you are under an earthly influence which will cause you to fall short from knowing God. Sensual influence will prevent you from desiring God when you are not under the sweet influence of the Holy Spirit. You will carry out your life like a beast, without boundaries and limits to your human depravities without the aid of the Holy Spirit.
“Wherein in time past ye walked according to the course of this world, according to the prince of the power of the air, the spirit that now worketh in the children of disobedience:” Ephesians 2:2
If you are not under the sweet influence of the Holy Spirit you open yourself up to devilish influences which will make you put into practice all the sins of the flesh.
These substitutes to the sweet influence of the Holy Spirit are not good for you or for anyone. You must open yourself up to receive the Holy Spirit so that He may influence you to BE HOLY.